“The great business of man's life, is to answer the end for which he lives;”
Penn frames a meaningful life in explicitly Christian terms: a person’s central task is to live toward the religious purpose for which Penn believes human life was given.
Source details
No Cross, No Crown, Preface, Project Gutenberg #44895. Penn opens by saying that the great business of life is to answer the end for which one lives, immediately defining that end as glorifying God and saving one’s soul. The frozen catalog retains only the opening clause. This is explicitly Quaker Christian devotional exhortation, not a neutral or universal factual definition of life’s purpose.